Breast Tissue Composition and Susceptibility to Breast Cancer
Norman F. Boyd, Lisa J. Martin, Michael Bronskill, Martin J. Yaffe, Neb Duric, and Salomon Minkin
JNCI 2010 102;16:1-14
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There is now a substantial body of evidence showing that the variations in breast tissue composition that are reflected by mammographic density have the characteristics of a highly heritable quantitative trait and are associated with differences in risk of breast cancer
Characterization of breast density by mammography has several limitations, and the uses of breast density in risk prediction and breast cancer prevention may be improved by other methods of imaging, such as magnetic resonance or ultrasound tomography
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